Because of the largely unrestricted insulin signaling, hyperinsulinemia increases the risk of obesity, type 2 diabetes, and cardiovascular disease and decreases health span and life expectancy. In epidemiological studies, high-dose insulin therapy is associated with an increased risk of cardiovascular disease.
Are you concerned about whether a vial contains bad insulin? Insulin can have a diminished ability to decrease blood sugar levels compared to what was expected. There are lots of discussions on the internet about how to identify bad insulin, so I'll focus on what to do with the insulin and the vial when you suspect you have bad insulin.
I'd like to point out that there are two different approaches with bad insulin: first, contacting the manufacturer or your pharmacy about returning suspected bad insulin, and second, deciding to discard a vial of partially used insulin. However, before contacting the manufacturer or tossing the vial, it is important to talk to your health team to check if your blood sugar is out of control because other medical reasons.
Bad insulin is not the only cause of high blood sugar. Contacting the Manufacturer or Pharmacy For many insulin products, the liquid that contains insulin should be clear and colorless. Therefore, if you open a box of this kind of insulin and find that the liquid in the vial is discolored, or that the liquid has particles floating in it, there's something wrong. In such a case, the insulin should not be used, and the manufacturer should be notified.
They will want to take back the vial and test it, and they will arrange for you to get a replacement vial. If it is cloudy or slightly colored, return it to your pharmacy for a replacement. Again, the insulin should not be used, and arrangements made to return the vial for replacement.
Is Insulin Good Or Bad?
There's another circumstance about bad insulin that might occur and doesn't quite qualify as the manufacturer's problem: insulin shipping problems before the vial gets to your possession. Ever since that episode, I've been concerned about the possibility of bad insulin that had been shipped in the heat of summer -- or the cold of winter. And if you get your insulin from a mail-order pharmacy, it might seem more likely that the on a shipping dock someplace or in a delivery truck.
I realize this is a risk for insulin delivered to your local pharmacy, as well as for insulin delivered to your door, but it seems more likely the more steps there are in the delivery chain. If you open a new vial of Is insulin good or bad? in mid-summer or mid-winter, and it just doesn't have the usual effect, maybe it was a shipping problem, rather than a manufacturing problem.
Insulin resistance resaults? good or bad : AskDocs
Take it back to the pharmacy, or call the mail-order pharmacy. If they won't help, call the manufacturer - and mention the local weather. Let's break these warnings into several categories. If you are storing your insulin in the Is insulin good or bad? conditions, you can expect your insulin to last that long, and probably longer, but the potency of the insulin will diminish with passing time.
It's up to you to watch the effectiveness of your insulin, whether inside or outside of the manufacturer's time window, and if you choose to use insulin that's outdated, it may or may not go bad. This is true both for opened and unopened vials: the labels give advice for both situations. Use the vial with extreme caution if outdated. Mixing Insulins: Some insulin products are not compatible with others. But the vials should still be okay to use unless you deliberately squirted one insulin type into the other vial; then toss that vial.
Other Considerations There are other situations that don't show up in the product labels that might encourage you to toss the vial. The most common, I suspect, is the feeling that every time you start a fresh vial of insulin, that the stuff is more potent than the dregs from the previous vial. That might indicate that the previous vial Is insulin good or bad? every vial you use is losing potency during the time you're using it, even if you are using optimal storage conditions.
This is difficult to be sure of unless you keep meticulous records, but if you think the vials are losing potency rapidly, the safest thing to do is to discard the vial before it's down to the last drop.
Exactly when to discard the vial is a cost-benefit decision: it's costly to toss the insulin, but the benefit of avoiding bad insulin may be worth it. Bad insulin is a problem that will remain with us, and it's unlikely that anyone will ever be able to quantify how often it happens.
But when it happens, it's not always necessary to toss the vial; it depends on the circumstances! Lastly, consider that your insulin might be still be good and consult Is insulin good or bad? doctor to Is insulin good or bad? if you might need to adjust your dose.